Although I take Enbrel, and MTX, neither one work as well as the Plaquenil and the fatigue and joint pain have returned full force. I had to get off of plaquenil as well b/c of toxicity and benign tumors behind my eyes. I'm just wondering if any of you here have had to stop taking Plaquenil and if so what you replaced it with? Not knowing what your dx is, I don't know what to tell you. I haven't found a replacement except that I started my cytoxan every month now. Plaquenil for limited scleroderma Plaquenil anxiety side effect Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It is not known how Plaquenil works but researchers believe that Plaquenil interferes with communication between cells within the immune system. Ultimately, it is thought to block proinflammatory. Plaquenil certainly has risks, though at the dose taken for Sjogren's they are relatively low. I've been on Plaquenil several times for a multiyear period, but never felt I got any benefit from it. Others here have had good results, and a few have had bad reactions. I don't know of a natural product that is chemically similar to plaquenil. Glenn Frey's death, tied in part to rheumatoid arthritis medications he was taking, is a 'wake-up call' about the dangers of powerful drugs used to treat the condition, a top doc says. It should push arthritis patients and their doctors to seek out safer available alternatives. I also seem to be having a lot of anxiety and I never had this before I stopped my Plaq Am I just losing my mind? All I can do is offer you my sympathy and suggest you talk to your rheumy or hope that others here have an answer for you. I found that some of my symtoms came back after I got off of plaquenil too but I never found something to really "replace it" unforntunately. Yes I do get some kind of strange migraines but without the pain??? (If anything) Since stopping it even the sun is now my worst enemy and I have had to get a pair of sun glasses.. Hi momto3, Wow, I hate to hear that you had to stop taking plaquenil. Since you're taking Enbrel and MTX, I suppose you have RA and I can't imagine having that and not being able to take plaquenil. I have suffered with migraines for thirty years and the only true relief I've ever gotten are from accupuncture and immitrex. I've had other problems as well but I don't think those would help you b/c they are more related to SLE. Natural alternatives to plaquenil Rheumatoid Arthritis Treatment Options Johns Hopkins Arthritis Center, Natural alternatives to Plaquenil - Sjogren's World Minocycline plaquenil lyme Research on Natural and Alternative Therapies. Researchers continue to explore the benefits of alternative and complimentary therapies. There have been a number of studies that show that tai chi and yoga are effective in improving physical function in adults with rheumatoid arthritis and fibromyalgia. Exercises like tai chi and yoga, which. When the Patient Insists on Natural Therapies.. Safe, Natural Alternatives to Arthritis Drugs Top Doc. Alternatives to Plaquenil DailyStrength. Compare Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Plaquenil rated 6.8/10 in overall patient satisfaction. Plaquenil Compared to Alternatives - I'm still searching for that magic "all natural" replacement since I cannot tolerate plaquenil. The stomach, liver & eye complications are too great to bear. and that's at the lowest, lowest dose. Anyway, guess I need to get into some deeper research about exactly what this drug does, and. However, you can also consult your doctor about reducing your symptoms with the help of these natural remedies. Keep in mind that so far, scientific support for that claim that any form of alternative medicine can treat lupus is lacking.