One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Chloroquine resistant p falciparum 10 mg methotrexate weekly with plaquenil Can you take plaquenil with lipitor Taking Hydroxychloroquine develop toxicity2 It’s rare for side effects to occur with Plaquenil if the medication is dosed properly Side effects Blurred vision, bull’s eye maculopathy, scotoma, vortex keratopathy, headache, accommodative dysfunction, whitening of eyelashes, phototoxicity3 Incidence Not Known. Blistering, peeling, loosening of the skin. blurred vision or other vision changes. chest discomfort, pain, or tightness. cough or hoarseness. dark urine. decreased urination. defective color vision. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Plaquenil adverse effect on retina Plaquenil Side Effects Common, Severe, Long Term -, Hydroxychloroquine Side Effects Common, Severe, Long Term. Is chloroquine safe in early pregnancyChloroquine nurses responsibilityHydroxychloroquine 200 mg brand name While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine. Improved vision screening tests and updated dosing guidelines are key to avoiding such complications. Protecting your eyesight when taking Plaquenil Lupus.. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. What can Hydroxychloroquine Plaquenil do to my eyes?. Hydroxychloroquine, an anti-malarial medication, is useful in treating several forms of malaria as well as various rheumatologic diseases, such as rheumatoid arthritis RA, 1 systemic lupus erythematosus SLE and dermatologic conditions. 2 Retinal toxicity is a well-known adverse effect associated with the use of chloroquine and. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.