It is very important that you keep your sugar under control. Very hard to control the lupus, but the sugar you have more ability to help with diet and exercise and meds. I don't like plaquenil Patient teaching on hydroxychloroquine Buy hydroxychloroquine sulphate Natural alternatives to hydroxychloroquine Thanks for your input, I appreciate it. My doctor ordered a bunch of blood tests, but I'm not sure if they checked blood sugar level or c-peptide; I'll have to ask next time I see her. When your symptoms were flaring, and you experienced the rapid heart rate, was your plaquinel increased? Concomitant PLAQUENIL and digoxin therapy may result in increased serum digoxin levels serum digoxin levels should be closely monitored in patients receiving combined therapy. Insulin or antidiabetic drugs As PLAQUENIL may enhance the effects of a hypoglycemic treatment, a decrease in doses of insulin or antidiabetic drugs may be required. Roger Austin, MS, RPh, CDE, responds Prednisone is a commonly prescribed corticosteroid steroid, for short. These drugs have also been called "glucocorticoids" because of their effects on glucose metabolism Increases in blood glucose are common among people taking prednisone and other steroids. I do not know if you are taking them, but most "lupies" do at one point or another. Taking steroids will play havoc on your sugar levels. Plaquenil increases sugar levels Hydroxychloroquine Plaquenil Side Effects & Dosage for., PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION Hydroxychloroquine dosing guidelinesPlaquenil for scarring alopeciaChloroquine clathrinBenefits drawbacks hydroxychloroquine Yes, plaquenil can cause low blood sugars. Eat frequent meals with carbs and protein but good carbs with fiber like oatmeal or whole wheat toast with peanut butter. I like the lowered blood sugar effect b/c I have type 2 diabetes but before I got type 2, I had some low sugars with plaquenil for sure. Plaquenil and low blood sugar -. Can Steroids Have a Lasting Effect on Blood Glucose.. Plaquenil - Uses, Side Effects, Interactions -. In this study, despite an increase in the serum insulin level, the glucose tolerance remained unchanged. Some authors concluded that both groups with normal glucose tolerance and impaired glucose tolerance had the same relative increase in insulin levels after oral glucose, indicating an equivalent beta-cell function. Well, the combination of high sugar levels and SLE is a one two punch to the kidneys. It is very important that you keep your sugar under control. Very hard to control the lupus, but the sugar you have more ability to help with diet and exercise and meds. Taking steroids will play havoc on your sugar levels. A favorable effect of hydroxychloroquine on glucose and lipid metabolism beyond its anti-inflammatory role. CQ increases insulin binding to its receptor and alters hepatic insulin metabolism. lower fasting blood sugar levels.