I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Synthesis of chloroquine from m-chloroaniline Can i take plaquenil at the same time as metformin Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Call your doctor at once if you have headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats; very slow heart rate, weak pulse; Also, communication with the prescribing doctor is very important. I have a form letter where I fill in the current dose, weight and goals.” Dr. Marmor “Stop the drug Plaquenil if you detect parafoveal thinning. But you do have to discuss this with the patient and his or her rheumatologist to be sure you’re not affecting the medical care. Plaquenil is supposed to stay in your system for 1-2 months after you stop taking it. Try to rest, stay hydrated and away from sick ppl for now and hopefully you will not have any issues Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Ddo you have to stop plaquenil slowly Plaquenil? I have been on prednisone for 15 months. - PMRGCAuk, Rx Side Effects New Plaquenil Guidelines and More - American. Does plaquenil cause hair growthGeneric plaquenil price increaseChloroquine for typhoidCan you take hydroxychloroquine and aspirinPlaquenil user reviews Those who stopped it abruptly had real problems similar to what you are experiencing. If you really need to get off it, I would taper down slowly, very slowly. There is a similar posting on Healthunlocked, "Why oh why did u stop taking plaquenil." You may want to check it out. Hydroxychloroquine plaquenil withdrawl? - LUPUS UK. Stopping Plaquenil - General Discussion - Life With Lupus. Stopping Methotrexate - Arthritis Information. Jan 27, 2010 The only thing I can think is that when you stop the plaquenil quickly one might have a flare that occurs "slam bam". If you taper off the flare may come anyway but maybe it would be slower and more mild. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Call your doctor at once if you have headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats; I was told I didn't have to taper it like prednisone, and that I shouldn't expect any rebound type of reaction like you get when your body adjusts to being off pred. But everyone is taking a different mix of drugs and maybe you're taking something I don't that would make your doctor's recommendation for you different.