In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Malaria medicine hydroxychloroquine Does hydroxychloroquine lower your immune system Plaquenil contraindications Hydroxychloroquine risks Disease Entity. International Classification of Disease ICD 2014 ICD-9-CM 362.53 Cystoid Macular Degeneration; Disease. The American Academy of Ophthalmology Preferred Practice Patterns defines Cystoid Macular Edema CME as retinal thickening of the macula due to a disruption of the normal blood-retinal barrier; this causes leakage from the perifoveal retinal capillaries and accumulation of. In order to protect the eyes, a baseline exam is recommended be- fore starting the drug if you are color blind, have prior retinal problems or have never had a dilated exam checking color vision is one way the doctor monitors for early damage or within the first 6-12 months if you have a history of healthy eyes and a recent retinal examination. At recommended doses, the risk of toxicity up to 5 years is under 1% and up to 10 years is under 2%, but it rises to almost 20% after 20 years. However, even after 20 years, a patient without toxicity has only a 4% risk of converting in the subsequent year. Major Risk Factors High dose and long duration of use are the most significant risks. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Plaquenil without macular signs icd 10 New Plaquenil Guidelines, Ask the Expert Plaquenil and Sjögren’s Plaquenil versus hydroxychloroquine The ICD-10-CM code H35.89 might also be used to specify conditions or terms like abnormal rod or cone threshold, absent foveal reflex, acute retinal necrosis, aminoquinoline antimalarial adverse reaction, angiomatosis of retina, atrophic retina, etc ICD-10-CM Code H35.89 - Other specified retinal disorders. Drug induced maculopathy - EyeWiki. Recommendations on Screening for Chloroquine. Chloroquine and hydroxychloroquine belong to the quinolone family. They are related drugs with similar clinical indications for use and similar manifestations of retinal toxicity, although their therapeutic and toxic doses differ. The risk of retinal toxicity was initially believed to be less than 1% after long-term or a cumulative dosage of 1,000mg. 3 The toxicity would double by 10 years, resulting in a 20% prevalence after 20 years. 4 However, research now shows toxicity continues even after cessation of the drug. 5 Thus preventing and detecting early effects of. Answer When billing Plaquenil examinations, or any other high risk medication exams, it is appropriate to bill the systemic disease or any ocular manifestations as the primary diagnosis since many payers may not reimburse for the high-risk medication diagnosis as a stand-alone diagnosis. Testing services performed should have the high-risk.