It is often the first line of attack before other more aggressive therapies are added such as methotrexate or rituximab that have bigger impacts on the immune system. I had almost (but not quite) forgotten what these aches and pains feel like, but they're back…I am re-acquainting myself with those symptoms that it tames: the overall flu-like and feverish feeling -- aka malaise -- and joint pain." (Click here to read more). I had a similar experience when I stopped taking plaquenil. Immunosuppressant plaquenil Bruises on shin from plaquenil The pharmacological profile of chloroquine and hydroxychloroquine, however, appear to involve mechanisms other than autophagy inhibition. Here, we discuss the dual role of autophagy in oncogenesis and tumor progression, and summarize the results or design of clinical studies recently completed or initiated to evaluate the therapeutic activity. Aug 14, 2017 Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. But there's evidence the drug can activate a virus that can increase the risk of lymphoma and similar cancers in some patients. Rheumatoid Arthritis Drug Linked to Cancer. Small Percentage. My joint and muscle pain went up and my energy levels went down. No, but it did alleviate some of the symptoms and improve my quality of life. It was one of those situations where I didn't realize the medication was having such an impact until I stopped it. Plaquenil and lymphoma Is it possible to have Lymphoma without many if not any., Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Plaquenil cause itchingWhat does plaquenil do for you In summary, patient #1, with a 10-year history of SLE and chronic hepatitis B, presented with primary CNS lymphoma PCNSL of leptomeningeal/spinal type and was treated successfully with high dose methotrexate and rituximab. Patient #2 had a 19-year long history of SLE and also presented with a localized CNS lymphoma. SLE and Non-Hodgkin’s Lymphoma A Case Series and Review of.. Rheumatoid Arthritis Drug Linked to Cancer - WebMD. Chloroquine & Hydroxychloroquine supporting chemo.. Plaquenil sometimes can cause lymphoma. My dads started out in his groin then went to his back and practically ate his. My dads started out in his groin then went to his back and practically ate his. Dr Bernatsky As is seen in the general population, lymphoma risk in SLE appears to be higher in men than women, and risk increases with age. A study conducted by our team examined demographic factors of patients with SLE who developed non-Hodgkin lymphoma. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis.