Clonidine sulfate

Discussion in 'Canadian Drug' started by scout313, 23-Aug-2019.

  1. bbk84 Moderator

    Clonidine sulfate


    Adrenergic receptor agonist, used as a "reliever" inhaler in the management of asthma symptoms and as a tocolytic (anti-contraction medication) to delay preterm labor for up to 48 hours. This time can then be used to administer steroid injections to the mother which help fetal lung maturity and reduce complications of prematurity. It should not be used to prevent preterm labor or delay labor more than 48–72 hours. In February 2011, the Food and Drug Administration has ordered to put a boxed warning on the drug's label. Pregnant women should not be given injections of the drug terbutaline for the prevention of preterm labor or for long-term (beyond 48–72 hours) management of preterm labor, and should not be given oral terbutaline for any type of prevention or treatment of preterm labor "due to the potential for serious internal heart problems and death." to delay premature labor. The inhaled form of terbutaline starts working within 15 minutes and can last up to 6 hours. Terbutaline as a treatment for premature labor is an off-label use not approved by the FDA. Agmatine is a chemical substance which is naturally created from the chemical arginine. Agmatine has been shown to exert modulatory action at multiple molecular targets, notably: neurotransmitter systems, ion channels, nitric oxide (NO) synthesis and polyamine metabolism and this provides bases for further research into potential applications. Agmatine was discovered in 1910 by Albrecht Kossel. It took more than 100 years to find the exact functions of the chemical. The term stems from A- (for amino-) g- (from guanidine) -ma- (from ptomaine) -in (German)/-ine (English) suffix with insertion of -t- apparently for euphony. Agmatine biosynthesis by arginine decarboxylation is well-positioned to compete with the principal arginine-dependent pathways, namely: nitrogen metabolism (urea cycle), and polyamine and nitric oxide (NO) synthesis (see illustration 'Agmatine Metabolic Pathways'). Agmatine degradation occurs mainly by hydrolysis, catalyzed by agmatinase into urea and putrescine, the diamine precursor of polyamine biosynthesis.

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    A comparative study between dexmedetomidine, clonidine and magnesium sulfate in attenuating hemodynamic response to laryngoscopy and intubation – a. Jan 26, 2017. Conclusion Clonidine and captopril represent safe, effective treatments. blood pressure DBP ≥110 mmHg, requiring magnesium sulfate. Aug 15, 2013. To compare the efficacy of clonidine versus phenobarbital in reducing morphine sulfate treatment days for neonatal abstinence syndrome.

    This medication is used alone or with other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Clonidine belongs to a class of drugs (central alpha agonists) that act in the brain to lower blood pressure. It works by relaxing blood vessels so blood can flow more easily. Take this medication by mouth with or without food as directed by your doctor, usually twice daily (in the morning and at bedtime). If the doses are not equal, take the larger dose at bedtime to decrease the risk of side effects. The dosage is based on your medical condition and response to treatment. There is insufficient evidence for the application of clonidine in children and adolescents younger than 18 years. Therefore the use of clonidine is not recommended in paediatric subjects under 18 years. Clonidine should not be used in patients with severe bradyarrhythmia resulting from either sick-sinus syndrome or AV block of 2nd or 3rd degree, or in patients with known hypersensitivity to the active substance or to any of the excipients listed in section 6.1. In case of rare hereditary conditions that may be incompatible with an excipient of the product (please refer to section 4.4. Special warnings and precautions for use) the use of this product is contraindicated. Clonidine should be used with caution in patients with cerebrovascular disease, coronary insufficiency, heart failure, occlusive peripheral vascular disorders such as Raynaud's disease, polyneuropathy, constipation or those with a history of depression. At doses higher than those recommended above, clonidine is an effective antihypertensive agent.

    Clonidine sulfate

    Agmatine sulfate salt ≥97%, powder Sigma-Aldrich, Clonidine versus Captopril for Severe Postpartum Hypertension A.

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  4. Kg bolus dose and magnesium sulfate infusion at 10 mg/kg/h, whereas the subjects in the. magnesium sulphate and clonidine on propofol consumption.

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    Clonidine hydrochloride is a centrally acting alpha-agonist hypotensive agent available as tablets for oral administration in three dosage strengths 0.1 mg, 0.2 mg and 0.3 mg. The 0.1 mg tablet is equivalent to 0.087 mg of the free base. Clonidine hydrochloride tablets USP contain the following. Stability of admixture containing morphine sulfate, bupivacaine hydrochloride, and clonidine hydrochloride in an implantable infusion system. Ashley M. Classen. OTHER NAMES Alcaloïde de Berbérine, Berberina, Berbérine, Berberine Alkaloid, Berberine Complex, Berberine Sulfate, Sulfate de Berbérine.br/br/

     
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