Additionally, another exception occurred while executing the custom error page for the first exception. Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Hydroxychloroquine retinal deposits How to pronounce chloroquine Synthesis of chloroquine from 4 7-dichloroquinoline Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so. Photopsia perception of flashes or flickering light, metamorphopsia distortion e.g. of straight lines and, in its later stages, reduced colour vision and peripheral field loss are also reported. Early. review of mfERG ring ratios in Plaquenil toxicity. Doc Ophthalmol. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Photopsia plaquenil toxicity The Risk of Retinal Toxicity with Plaquenil - Sjogren's, Protecting your eyesight when taking Plaquenil Lupus. Sar of chloroquine pptCan i take advil cold and sinus with hydroxychloroquinePlaquenil help payingWhat drug class is hydroxychloroquine It is a derivative chloroquine, also an antimalarial agent which has a much higher risk of toxicity. Plaquenil can rarely cause a retinal problem involving the central visual area, or macula. Retinal toxicity from Plaquenil is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Medications that can Affect the Eye or Visual System. Hydroxychloroquine-related retinal toxicity Rheumatology.. Hydroxychloroquine-related retinal toxicity Rheumatology Oxford.. A 57-year-old woman was referred to a retinal specialist with concerns of ocular toxicity from hydroxychloroquine. She complained of blurry vision and flashing lights photopsia. The patient had been taking 400 mg of hydroxychloroquine daily for 10 years for the management of systemic lupus. This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. Commonly used on holidays in malaria prone destinations, chloroquine and hydroxychloroquine will not be over familiar to the emergency physician. However, it is one of the leading causes of drug overdose in malaria prone countries and also the occasional toddler has managed to consume the grandparents lupus or rheumatoid arthritis medication leading to lethal consequences.