Regardless of the problem, we'd like to help you find what you're looking for. Interferes with digestive vacuole function within sensitive malarial parasites by increasing the p H and interfering with lysosomal degradation of hemoglobin; inhibits locomotion of neutrophils and chemotaxis of eosinophils; impairs complement-dependent antigen-antibody reactions Incomplete and variable (~70% [range: 25 to 100%]) (Tett 1993) Hepatic; metabolites include bidesethylchloroquine, desethylhydroxychloroquine, and desethylchloroquine (Mc Chesney 1966) Urine (15% to 25% [Tett 1993]; as metabolites and unchanged drug [up to 60%, Mc Chesney 1966]); may be enhanced by urinary acidification Rheumatic disease: May require several weeks to respond ~40 days (Tett 1993) ~40%, primarily albumin (Tett 1993) Lupus erythematosus: Treatment of chronic discoid erythematosus and systemic lupus erythematosus in adults. Plaquenil calculator Chloroquine drug action Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Hydroxychloroquine dosing information. Usual Adult Dose for Malaria Treatment of the acute attack 800 mg 620 mg base followed in 6 to 8 hours by 400 mg 310 mg base, then 400 mg 310 mg base once a day for 2 consecutive days; alternatively, a single dose of 800 mg 620 mg base has also been effective Side Effects. Drug information provided by IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Limitations of use: Hydroxychloroquine is not effective against chloroquine- or hydroxychloroquine-resistant malaria strains of Plasmodium species; not recommended for treatment of complicated malaria, malaria prophylaxis in regions with chloroquine resistance, or treatment when the Plasmodium species has not been identified; hydroxychloroquine does not prevent relapses of P. ovale infections because it is not effective against the hypnozoite forms of these parasites. Malaria: Treatment of uncomplicated malaria caused by susceptible strains of Plasmodium vivax, Plasmodium malariae, Plasmodium ovale, and Plasmodium falciparum; prophylaxis of malaria in geographic areas where chloroquine resistance is not reported. Hydroxychloroquine sulfate 200 mg brand name Hydroxychloroquine - Side Effects, Dosage, Interactions., Hydroxychloroquine Uses, Dosage & Side Effects - Hydroxychloroquine skin peelingHydroxychloroquine porphyria cutanea tarda mechanismLong-term progression of hydroxychloroquine retinopathy off the drug marmorHow much is plaquenil without insurance for genericPill plaquenil generic dog bone shapped The recommended hydroxychloroquine dosage for rheumatoid arthritis is 400 mg to 600 mg a day by mouth as a single dose or divided into two separate doses. However, once a good response is being maintained with hydroxychloroquine, doses may be reduced to 200 mg to 400 mg per day for maintenance. Hydroxychloroquine Plaquenil Success, Reviews and Side Effects. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Hydroxychloroquine Sulfate Tablets, USP - Teva Generics. The generic medication, which is sold by the name hydroxychloroquine, is only available in a 200 mg strength. The FDA has determined that all generic Plaquenil products currently available are equivalent to the brand-name version of the drug. Hydroxychloroquine is taken in tablet form, with or after food. Your doctor will advise you about the correct dose. Usually you will start on a full dose of 200–400 mg daily, and later your doctor may reduce this. When your condition is very well controlled you may be advised to take hydroxychloroquine only 2–3 times per week. A 25 mg/mL hydroxychloroquine sulfate oral suspension may be made with tablets. With a towel moistened with alcohol, remove the coating from fifteen 200 mg hydroxychloroquine sulfate tablets. Crush tablets in a mortar and reduce to a fine powder.