Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine side effects rash Does plaquenil cause headaches Concurrent administration of chloroquine On examination, a telltale sign of hydroxychloroquine toxicity is a bilateral change in the retinal pigment epithelium of the macula that gives the commonly described appearance of a bull’s-eye. This is a late finding, however, and too late for screening to be useful. Skin Hyperpigmentation with Hydroxychloroquine Hydroxychloroquine Plaquenil is a common trade name is an anti-inflammatory oral medication that is commonly used to treat many autoimmune diseases. In the hair clinic, we use it for diseases such as lichen planopilaris, frontal fibrosing alopecia, Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Stopping plaquenil change to what Lupus Medicines Hydroxychloroquine - Brigham and Women's., Skin Pigmentation with Hydroxychloroquine Plaquenil. Plaquenil and vaccinesCan you take plaquenil with leaky gutPlaquenil antimalarialIs hydroxychloroquine an anti malarial medicationHydroxychloroquine rxlist One of the problems with Plaquenil is that because it's so slow to act, the improvements are also slow and subtle. So most people don't realize that they've improved until they STOP taking it. I've been on it twice, along with Atabrine another antimalarial. In my case, it never worked so I didn't notice a change. Stopping plaquenil. DailyStrength. Plaquenil Uses, Dosage & Side Effects -. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Yes you can stop it without weaning. My Rheumy had me do it after I had been on it 3-4 months because I developed ringing in my ears. I didn't have any problem stopping, but did start a flare though which she warned me might happen. The ear ringing didn't really change so eventually at least 6 months later I started Plaquenil again. Since the side effect of vision loss is possible but rare, it is important for you to tell your doctor about any vision changes that you experience. Doctors generally recommend regular eye exams while on Plaquenil, so that early changes can be caught. Once abnormalities are discovered, toxicity has already occurred. I recently decided to stop taking Plaquenil because I was having constant chest pains even more so than I usually have due to Lupus. Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Also I noticed that the Plaquenil I think was making me feel different but not in a good way.