Keep in mind that most people with Sjogren's stay healthy and don't have serious problems. You should be able to keep doing all the things you love to do without making many changes. Hydroxychloroquine and metformin Hydroxychloroquine and myasthenia gravis Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Plaquenil is a drug used to treat Rheumatoid Arthritis and Systemic Lupus Erythematosis. It is a very good drug and gives many patients significant relief from their symptoms. Plaquenil related eye complications are not common. Plaquenil can produce pigment changes in the macula of the retina. Summary Dry mouth is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Enbrel, and have Osteoporosis. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration. Conditions like this are called autoimmune diseases. Sjogren's causes your immune system to go haywire and attack healthy cells instead of invading bacteria or viruses. Plaquenil causes dry eyes Common and Rare Side Effects for Plaquenil Oral, Conditions Plaquenil-related Eye Problems Eugene Eye Care Plaquenil retinopathy info for patientLow-dose hydroxychloroquine role in porphyriaQue es el medicamento plaquenilHydroxychloroquine sulfate tab actaPlaquenil 200mg là thuốc gì Do you think the Raynaud's phenomenon is related to my dry eyes? I ask this because so far these seem to be the only two confirmed issues that point to Sjogren's and the former started occurring many, many years ago, while the dry eyes about three years ago. Do you think it is the right stage of diagnosis of Sjogren's to take Plaquenil? Dry eyes, Sjogrens and Plaquenil. DailyStrength. Will you have Dry mouth with Plaquenil - eHealthMe. Ask the Expert Plaquenil and Sjögren’s. A 57-year-old female presented to the Ophthalmology clinic at UIHC complaining bilateral central photopsias for the past two years. She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine Plaquenil 200mg bid 6.5mg/kg for 10 years, which was stopped one year prior to. Sjögren's syndrome with gland inflammation resulting dry eyes and mouth, etc. that is not associated with another connective tissue disease is referred to as primary Sjögren's syndrome. Sjögren's syndrome that is also associated with a connective tissue disease, such as rheumatoid arthritis, systemic lupus erythematosus, or scleroderma, is referred to as secondary Sjögren's syndrome. The vast majority of patients on Plaquenil get absolutely no eye problems and you should not be unduly worried or concerned. If you have a good response in your arthritis to the Plaquenil then the benefits of a Plaquenil almost certainly outweigh the small risks to your eyes.