Hydroxychloroquine for dermatomyositis

Discussion in 'Chloroquine' started by alez, 28-Feb-2020.

  1. Shad0w Moderator

    Hydroxychloroquine for dermatomyositis


    Although the disorder is rare, with a prevalence of one to 10 cases per million in adults and one to 3.2 cases per million in children, early recognition and treatment are important ways to decrease the morbidity of systemic complications. Dermatomyositis is an idiopathic inflammatory myopathy with characteristic skin manifestations.

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    Background/Purpose Hydroxychloroquine is an antimalarial agent commonly used in the treatment of rheumatologic diseases. Data on the use of HCQ in JDM is limited, primarily based on anecdotal experience and two small, retrospective reviews. As a result, there is no current consensus on the utility of HCQ in the management of JDM. Prednisone is the first-line therapy for muscle involvement in dermatomyositis. The dose is altered according to the response of the patient’s condition. Antimalarials, particularly hydroxychloroquine, may be useful for cutaneous disease; however, the majority of patients with cutaneous involvement require additional. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.

    Poor prognostic indicators include poorly responsive disease, delay in diagnosis and the presence of malignancy. Patient management includes careful evaluation for underlying malignancy and liberal use of physical therapy, antihistamines, sunscreen and oral corticosteroids.

    Hydroxychloroquine for dermatomyositis

    Dermatomyositis DermNet NZ, Dermatomyositis Medication Disease-Modifying.

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  4. In a recent study published in JAMA Dermatology, researchers aim to assess if skin eruptions that develop during hydroxychloroquine sulfate use are associated with autoantibodies in dermatomyositis. This cohort study used 111 patients with dermatomyositis treated with hydroxychloroquine.

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    The reason hydroxychloroquine has been considered a ‘first-line’ therapy for cutaneous dermatomyositis for years is essentially because it is a ‘first-line’ therapy for skin disease in lupus,”. Dermatomyositis is a disease that causes rash and muscle weakness. Learn more about the symptoms, causes, and treatments of this condition. Antimalarial medicines like hydroxychloroquine treat. Hydroxychloroquine sulfate Plaquenil Mechanism not understood; used in arthritis, lupus, malaria; can be used to reduce steroid dosage in myositis, particularly in children. Can treat muscle symptoms and dermatomyositis rash. Can cause damage to eyes’ retinas or corneas; regular eye exams needed. infusion of mixed immunoglobulins; IVIg

     
  5. kordara Moderator

    The resource you are looking for (or one of its dependencies) could have been removed, had its name changed, or is temporarily unavailable. Positive ANA test 0 but negative for all Autoimmune. ANA Negative Systemic Lupus Erythematosus Leading to CTEPH. Is It Common to Have Lupus with a Negative ANA Test?
     
  6. Woozle New Member

    I dropped my dose from 2 down to 1 for the past 3 (going on 4) days, and I am already miserable. How long before your hair started coming back and you began feeling better? I have been SOOOO tempted to reach for that evening dose today. How long does Hydroxychloroquine stay in your system? Hydroxychloroquine - Wikipedia Treatment of hydroxychloroquine overdose - ScienceDirect
     
  7. yuci Moderator

    Plaquenil Indications, Side Effects, Warnings - Oct 22, 2019 What are some other side effects of Plaquenil? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away Dizziness. Headache. Feeling nervous and excitable. Not hungry.

    Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.
     
  8. 90210 New Member

    Hydroxychloroquine and the immune system Hi everyone. - NRAS Suppressed Immune system because of steroids and 12.5 methotrexate. Thanks Immune system happy Christmas to you too. Oral surgeon says \"Breeding ground for bacteria\" and \"your immune system must be taking a beating\" Hydroxychloroquine ; Hydroxychloroquine

    Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.