Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Plaquenil sun sensitivity tingling Hydroxychloroquine with or without food Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. For this reason, you can think of antimalarials as a sort of “lupus life insurance.” My ANA stays negative and he says that because I don't have severe disease and due to being on the plaquenil that my ANA is staying negative. You do need to ensure you are having eye exams every 6 months and tell your eye doctor you are on plaquenil. Hydroxychloroquine is a DMARD. The brand name is Plaquenil. What does Plaquenil do? Plaquenil relieves pain and swelling and prevents damage to joints. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Ana and plaquenil Antinuclear Antibodies ANA, Can Plaquenil cause a false negative ANA - Lupus - MedHelp Lichen planopilaris plaquenilHydroxychloroquinHydroxychloroquine lymphadenopathy Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. Hydroxychloroquine Plaquenil. Doctors give trusted answers on uses, effects, side-effects, and cautions Dr. Friedlander on positive ana on plaquenil One of the things that's frustrating about these antibody tests looking for different connective tissue diseases is that they are difficult to do and are fraught with pitfalls. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. My symptoms most resemble lupus, but positive ANA is the only specifically associated test that is consistantly positive, other than off and on elevations in Sed rate, CRP and liver enzymes. I had one very mildly positive rheumatoid factor.