It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil for atopic dermatitis Scleroderma plaquenil Plaquenil and early menopause After these drugs were abandoned for the treatment of malaria, more study was done, and they were found to be effective for discoid lupus, subacute cutaneous lupus, dermatomyositis, rheumatoid arthritis, and psoriatic arthritis. Plaquenil has a better safety profile than chloroquine and is most commonly used today. Yeast infections in the mouth should be treated with antifungal medications. Treat systemwide symptoms. Hydroxychloroquine Plaquenil, a drug designed to treat malaria, is often helpful in treating Sjogren's syndrome. Drugs that suppress the immune system, such as methotrexate Trexall, also might be prescribed. Surgery Originally developed as a chemotherapy drug to treat cancer and used as an immunosuppressant to treat lupus. Known as the "gold standard" -- the best drug -- for the treatment of rheumatoid arthritis. Shown to be very effective in treating skin lesions, arthritis and pleuritis in people with lupus. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil to treat mouth disease Lichen planus - Diagnosis and treatment - Mayo Clinic, Sjogren's syndrome - Diagnosis and treatment - Mayo Clinic Hydroxychloroquine toxic retinopathyComing off hydroxychloroquinePlaquenil and atrial fibrillationNeurological side effects of plaquenil It has not helped me yet with my mouth and lips or being tired but since I haven't reached the six month mark I still have hope. I am with the others and encourage you to start Plaquenil. I think you will feel much better and slowing the progression of this disease is important. Treatment/Plaquenil -. Medications used to treat lupus Lupus Foundation of America. Hand, Foot, and Mouth Disease HFMD CDC. Plaquenil hydroxychloroquine is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s. While there is good clinical evidence demonstrating. WebMD explains the causes, symptoms, and treatment of Sjogren's syndrome, a condition in which your eyes, mouth, and other parts of your body get dried out. The Sjogren’s Syndrome Foundation has issued the first-ever treatment guidelines for systemic Sjogren’s syndrome, a disease that affects as many as 6 million people in the U. S. with or without connective tissue disease.