The technological growth in ocular imaging has allowed for profound advancements in the clinician’s ability to recognize subtle abnormalities, differentiate stability from progression in ocular pathology and identify disease stages. Clinicians have four prominent commercially available spectral-domain (SD) OCT models to choose from: Spectralis SD-OCT (Heidelberg Engineering), 3D OCT-2000 (Topcon Medical Systems), Avanti RTVue XR (Optovue), and Cirrus HD SD-OCT 5000 (Carl Zeiss Meditec). Hydroxychloroquine sulfate adverse effects Plaquenil treats graves Plaquenil dose for sjogrens OCT Interpretation in Retinal Disease. Cirrus 5000 –100X Raster - EDI 350 microns 450 microns Central Serous Retinopathy. 54 year old woman taking Plaquenil Ganglion Cell Complex The retinal ganglion cell and inner plexiform complex is more sensitive to the demyelination Although hydroxychloroquine retinal toxicity is thought to be rare, recent studies suggest it may have a higher prevalence than previously recognized. A large study examining patients with more than 5 years of HCQ use were evaluated with 10-2 visual fields or spectral-domain optical coherence tomography SD OCT. Figure 1 SD-OCT scan of a normal right eye. The vitreous, retinal layers and choroidal layers are visible. This scan was acquired with the Cirrus SD-OCT with 5-line raster set at 9mm with enhanced depth imaging EDI. Vitreous. The posterior hyaloid of the vitreous can be identified on macula scans especially with spectral-domain SD-OCT. While the earliest time-domain (TD) OCT technology could only acquire 400 scans per second, current SD-OCT models, depending on the manufacturer, can capture between 26,000 and 70,000 axial-scans per second (With eye tracking capability and image registration, artifacts are much less common than in prior technology. This article outlines the basics of OCT imaging and walks you through how to analyze retinal nerve fiber layer (RNFL) thickness, macular thickness and ganglion cell complex using each model. 5 line raster oct plaquenil Plaquenil Guidelines Point Out New Risks, New Presentation., Hydroxychloroquine Plaquenil Toxicity and Recommendations for Screening Plaquenil 200 mg miamiPlaquenil dose for discoid lupus We elected not to discontinue the Plaquenil therapy; however, we will follow her annually with 10-2 visual fields, SD-OCT and FAF. We gave the patient a written report and referred her to a rheumatologist for evaluation. 1. Marmor MF, Kellner U, Lai TY. Revised recommendations on screening for chloroquine and hydroxychloroquine retinopathy. Pause the Plaquenil?. Anatomy Review - Optical Coherence Tomography Scans. Simple Rules for Coding OCT. Hydroxychloroquine HCQ has been used for therapy of rheumatologic disorders since the 1950s. Ocular toxicity associated with HCQ use was initially described in the 1960s 1, 2incidence of HCQ retinopathy is estimated at 1 % after consumption of HCQ for 5 years is marked by paracentral and central scotoma and decreased color vision. Aug 30, 2011 Although hydroxychloroquine retinal toxicity is thought to be rare, recent studies suggest it may have a higher prevalence than previously recognized. A large study examining patients with more than 5 years of HCQ use were evaluated with 10-2 visual fields or spectral-domain optical coherence tomography SD OCT. Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.