It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Hydroxychloroquine vs truvada Anti-malarial medicine for chloroquine resistant malaira Hydroxychloroquine pericarditis Chloroquine syrup dosage for infants My rheumy has just prescribed Plaquenil for my SS. Reading the warnings, I see that there is concern about effects on the eyes retinas. I am very concerned about this and am wondering if anyone out there has been put on an alternative drug to treat their SS. I have several issues with my. Compare Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Plaquenil rated 6.8/10 in overall patient satisfaction. Plaquenil Compared to Alternatives - Quinacrine Atabrine is another alternative, but it is prescribed less often because it can sometimes cause a yellow discoloration of the skin. It is sometimes given in addition to hydroxychloroquine if the patient does not respond to Plaquenil alone. For prolonged treatment of lupus or arthritis, adverse effects include the acute symptoms, plus altered eye pigmentation, acne, anaemia, bleaching of hair, blisters in mouth and eyes, blood disorders, convulsions, vision difficulties, diminished reflexes, emotional changes, excessive coloring of the skin, hearing loss, hives, itching, liver problems or liver failure, loss of hair, muscle paralysis, weakness or atrophy, nightmares, psoriasis, reading difficulties, tinnitus, skin inflammation and scaling, skin rash, vertigo, weight loss, and occasionally urinary incontinence. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. For short-term treatment of acute malaria, adverse effects can include abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting. Plaquenil similar Hydroxychloroquine Plaquenil, Plaquenil Compared to Alternatives - Natural alternatives to plaquenil Hi, Carole. When I started Plaquenil, my GI system was in an uproar. But it usually was anyway. I didn't realize, until I saw Dr. Wallace's book and found the stats, plus my rheumie telling me much the same, that many people with lupus something like 40% or more "present" with GI problems. Natural" alternative to Plaquenil. - HealthBoards. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Safe, Natural Alternatives to Arthritis Drugs Top Doc. Substitutes and alternatives to Plaquenil hydroxychloroquine for uses like Rheumatoid arthritis, Lupus and Malaria Plaquenil hydroxychloroquine Alternatives & Similar Drugs - Skip to full site navigation Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. Plaquenil, Quineprox Methotrexate LPF Sodium, Otrexup, Rasuvo, RediTrex, Rheumatrex Dose Pack, Trexall, Xatmep N/A. Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. N/A. 12 hours. 11 hours. CSA Schedule** View glossary of terms.