« Mirapex / Requip / Neupro: Significant Increased Risk Of Compulsive Behaviors -- Gambling, Shopping, And Sex -- For These Parkinsons And Restless Leg Drugs | Main | The Link Between Popular Erectile Dysfunction (ED) Drug Viagra And Melanoma Has A Potential Molecular Basis According To Medical Expert Who Reviewed Recent Study » (Posted by Tom Lamb at Drug Injury Watch.com) While generally thought of as an antidepressant drug, Cymbalta (duloxetine) from Eli Lilly and Company has been approved by the FDA for use by patients diagnosed with: Major Depressive Disorder; Generalized Anxiety Disorder; Diabetic Peripheral Neuropathic Pain; Fibromyalgia; and, Chronic Musculoskeletal Pain Based on prescriptions for these several medical conditions and others -- by means of so-called "off-label" prescribing -- Cymbalta became a blockbuster drug for Lilly after being approved by the FDA in 2004. The first generic versions of Cymbalta were approved by the FDA on December 11, 2013. The Prescribing Information, or drug label, for Cymbalta (duloxetine) (accessed 10/27/14) indicates that stopping this drug is no more problematic than other SSRIs and SNRIs (serotonin and norepinephrine reuptake inhibitors). From this section of the label, 5.7 Discontinuation of Treatment with Cymbalta: Discontinuation symptoms have been systematically evaluated in patients taking duloxetine. Following abrupt or tapered discontinuation in placebo-controlled clinical trials, the following symptoms occurred at 1% or greater and at a significantly higher rate in duloxetine-treated patients compared to those discontinuing from placebo: dizziness, headache, nausea, diarrhea, paresthesia, irritability, vomiting, insomnia, anxiety, hyperhidrosis, and fatigue. During marketing of other SSRIs and SNRIs (serotonin and norepinephrine reuptake inhibitors), there have been spontaneous reports of adverse events occurring upon discontinuation of these drugs, particularly when abrupt, including the following: dysphoric mood, irritability, agitation, dizziness, sensory disturbances (e.g., paresthesias such as electric shock sensations), anxiety, confusion, headache, lethargy, emotional lability, insomnia, hypomania, tinnitus, and seizures. Although these events are generally self-limiting, some have been reported to be severe. We have received so many complaints about duloxetine side effects that we have lost count. Far more disturbing are the number of people who tell us how hard it is to discontinue this drug. Decades ago doctors might have told patients taking a drug like Cymbalta that if they experienced anxiety, irritability or strange sensations after stopping the drug, it was probably their underlying psychological problem returning. Cymbalta was originally approved by the FDA in 2004 for the treatment of major depression. In doctorspeak that means it is a serotonin-norepinehprine reuptake inhibitor and is somewhat similar to other antidepressants such as Effexor (venlafaxine) and Pristiq (desvenlafaxine). The FDA also approved Cymbalta to treat nerve pain associated with diabetes in 2004. In 2007 the drug got a green light for anxiety and in 2008 the FDA agreed that it could ease the discomfort associated with fibromyalgia. It was also approved to treat musculoskeletal pain associated with arthritis and lower back pain in 2010. In other words, here was a drug that could relieve your blues and your aches and pains. Metoprolol tartrate vs metoprolol succinate Cheap viagra express delivery Azithromycin 2g Buy bactrim online uk Unfortunately, few physicians know about Cymbalta Discontinuation Syndrome or how to manage withdrawal symptoms if they occur. Because Cymbalta is. Oct 27, 2014. From a preview in the front of this QuarterWatch publication concerning that "Duloxetine CYMBALTA and Serious Withdrawal Symptoms". Apr 4, 2018. Most antidepressant drugs are associated with some withdrawal symptoms. However, withdrawal symptoms from Cymbalta are so common that. Boyd Bergeson has been writing since 2000 and has contributed to published research with the National Institute of Health and The Indian Health Board. Bergeson is currently a mental health professional and has worked as a university instructor, senior medical research assistant, textbook editor, and bicycle shop owner. He has a Master of Science in sociology from Portland State University. View Full Profile Patients that discontinue Cymbalta may experience several psychological symptoms. These can take place within 24 hours after discontinuation and may last one to three days, but may last up to three weeks. The most common symptoms of atypical antidepressant withdrawal, including Cymbalta, are anxiety and low mood, such as apathy and rebound depression. Because Cymbalta strongly affects serotonin, after discontinuation it can take several days for the body's own serotonin system to return to normal. As my long-time readers know, I’ve been closely following the lawsuits related to Cymbalta’s withdrawal symptoms on Fed Upwith I was recently asked by to update their readers on the Cymbalta lawsuits. I’m reprinting that story here with the editor’s permission. Update 10/25/16: The Cymbalta lawsuits have been settled. When Lori Peterson’s doctor decided to switch her fibromyalgia medication from Cymbalta to Savella, she trustingly followed his instructions – a move that would land her on the couch for a week as she experienced Cymbalta’s withdrawal symptoms. Diagnosed with fibromyalgia in 2007, Peterson had been using Cymbalta for three years and was taking 60 mg twice a day. While Cymbalta eased her symptoms for a while, it had stopped working, and Peterson was hoping Savella would finally bring some relief from the pain and fatigue of fibromyalgia. “[My doctor] actually told me that I didn’t need to wean off of the Cymbalta as Savella was similar,” Peterson recalls. Duloxetine withdrawal side effects How long will I be going thru Cymbalta withdrawals? -, Some Patients Who Stopped Taking Cymbalta Have Suffered From. Hydrocortisone to prednisoneWhat are doxycyclineCiprofloxacin hplcCheap alternative to lexapropurchase lisinopril Apr 28, 2014. Symptoms of Cymbalta withdrawal may include Nausea and. Alcohol may increase some serious side effects of Cymbalta. Cymbalta may. Cymbalta Duloxetine - Side Effects, Dosage, Interactions - Drugs. Cymbalta - Cause For Concern? -. Cymbalta's withdrawal symptoms prompt lawsuits Fed Up with Fatigue. Sep 16, 2015. To be fair, the first time I took myself off Cymbalta, it was less of a “took myself. Also, honestly, I really did think the withdrawal symptoms would. Oct 15, 2012. The anti-depressant Cymbalta duloxetine can cause a host of side effects, but stopping the drug could also provoke unpleasant withdrawal. Cymbalta, clinically known as duloxetine, is a prescription medication indicated for the treatment of depression, anxiety, diabetic neuropathic pain and.