Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Will plaquenil help with memory Malaria resistance to chloroquine Mar 31, 2011 I have Lupus, Fibromyalgia and RA. Is it okay to take melatonin to help me sleep? Asked by svarnell Updated 30 August 2011 Topics rheumatoid arthritis, fibromyalgia, sleep disorders, melatonin, sleep, systemic lupus erythematosus Of note, a study demonstrated no significant difference in hydroxychloroquine serum concentration in patients taking concomitant antacids n = 14 compared to those not taking antacids n = 495. Canagliflozin Moderate Careful monitoring of blood glucose is recommended when hydroxychloroquine and antidiabetic agents, including the SGLT2 inhibitors, are coadministered. Take hydroxychloroquine with a meal or a glass of milk. To prevent malaria Start taking the medicine 2 weeks before entering an area where malaria is common. Continue taking the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Taking melatonin with hydroxychloroquine Melatonin - Mayo Clinic, Plaquenil hydroxychloroquine sulfate dose, indications. Buy hydroxychloroquine Even anti-malarials, such as hydroxychloroquine, can cause sleep difficulties and strange dreams. Taking such medications earlier in the day can be helpful in mitigating these effects. This, of course, must be discussed with your physicians. Alternately, some medications can be used to help you sleep. How To Get a Good Night's Sleep - HSS.edu. Hydroxychloroquine - Side Effects, Dosage, Interactions.. Interactions between Calcium-Melatonin Oral and di-trivalent.. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. Hydroxychloroquine received an overall rating of 7 out of 10 stars from 368 reviews. See what others have said about Hydroxychloroquine, including the effectiveness, ease of use and side effects. I am on Methotrexate and plaquenil, that help with the aches and pains. I also take 3 mgs of melatonin just before bed which helps so much, it may take a week or so before it is truly effective, I still wake early about 5 am but have learned to just lay and relax till time to get up.