Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Side effects plaquenil tablets Plaquenil toxicity ideal body weight Plaquenil eye exam protocol Long-term ≥5 years treatment with hydroxychloroquine include daily doses greater than 6.5 mg/kg 5 mg/kg base of actual body weight, subnormal glomerular filtration rate, durations of use longer than five years, and concurrent treatment with tamoxifen citrate. QT interval prolongation = torsades de pointes. ECG VF. TCA NA. HCTZ = electrocardiogram = ventricular fibrillation = tricyclic antidepressant = not applicable = hydrochlorothiazide. a Associations are based on the strength of evidence that supports whether QT prolongation can occur. This categorization does not delineate an DRUGS TO BE AVOIDED BY CONGENITAL LONG QT PATIENTS CredibleMeds® has reviewed all available evidence and has placed the following drugs in designated risk categories for their risk of causing torsades de pointes TdP Known Risk Hydroxychloroquine may also be used for purposes not listed in this medication guide. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine long qt Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Drugs Associated with QT Interval Prolongation Quinacrine with hydroxychloroquine lupus profundusPlaquenil and allergiesCorneal pics chloroquine side effectsAct chloroquine Chronic hydroxychloroquine use associated with QT prolongation and refractory ventricular arrhythmia. Clin Toxicol Phila. 2006; 442173-5 ISSN 1556-3650 Chen CY; Wang FL; Lin CC. BACKGROUND Hydroxychloroquine HCQ is used for treatment of lupus erythematosus. The cardiac toxicity of HCQ has focused primarily on acute intoxication. Chronic hydroxychloroquine use associated with QT.. DRUGS TO BE AVOIDED BY CONGENITAL LONG QT PATIENTS. Hydroxychloroquine Uses, Dosage & Side Effects -. Not for administration with other drugs that have potential to prolong QT interval; hydroxychloroquine prolongs QT interval; ventricular arrhythmias and torsades de pointes reported in patients taking hydroxychloroquine Skeletal muscle myopathy or neuropathy leading to progressive weakness and atrophy of proximal muscle groups. QT Interval prolongation Hydroxychloroquine has the potential to prolong the QTc interval in patients with specific risk factors. Hydroxychloroquine should be used with caution in patients with congenital or documented acquired QT prolongation and/or known risk factors for prolongation of the QT internal such as • advanced age, Long-term use and high doses of hydroxychloroquine are risk factors for the development of cardiomyopathy. Cardiac failure, conduction disorders including QT prolongation and Torsades de Pointes and sudden cardiac death are consequences of the cardiomyopathy.