B, Brown pigmentation on the legs in another patient who had systemic lupus erythematosus associated with diffuse discoid lupus. The skin biopsy was performed on the brown area distant from discoid lesions. How to spell plaquenil Incidence of retinal toxicity from plaquenil Hydroxychloroquine lupus mechanism Chloroquine maculopathy A 57-year-old woman with systemic lupus erythematosus and Sjögren syndrome presented with blue-grey hyperpigmentation of the face, upper back, and dorsal aspects of the feet after seven years of. Background/Purpose To describe the clinical features and outcome of hydroxychloroquine-induced pigmentation in patients with systemic lupus erythematosus SLE. Method This was a retrospective, monocentric SLE clinic, Pitié-Salpêtrière, Paris study of SLE patients with pigmented lesions considered to be related to hydroxychloroquine HCQ. In our case, infrared spectroscopy enabled us to identify meropenem in the dermis. Two cases of cutaneous hyperpigmentation have been reported following use of levofloxacin, and the results of histological examination were similar. This is the first case of cutaneous hyperpigmentation induced by meropenem. B, Presence of iron in the same areas of the dermis (Perls staining, original magnification ×100). Pub Med Google Scholar Crossref Morrison LK, Nordlund JJ, Heffernan MP. Pub Med Google Scholar Costedoat-Chalumeau N, Galicier L, Aumaître O, et al; Group PLUS. Google Scholar Costedoat-Chalumeau N, Amoura Z, Hulot JS, et al. Pub Med Google Scholar Crossref Costedoat-Chalumeau N, Leroux G, Piette J-C, Amoura Z. A, Interstitial and perivascular brown pigmented granules in the dermis (hematoxylin-eosin-safran staining, original magnification ×100). Woman in grey hydroxychloroquine-induced hyperpigmentation Hydroxychloroquine-related skin discoloration CMAJ, Talk Hydroxychloroquine-Induced Hyperpigmentation in. Keyhole macula chloroquineDizziness and plaquenil An elderly woman presented with 6 months history of skin coloured to erythematous papules in annular pattern over extremities, upper back and neck. The patient was diagnosed with granu-loma annulare GA and started on hydroxychlo-roquine HCQ 300 mg daily. After 4 months of treatment, she developed bluish grey pigmentation Hydroxychloroquine induced cutaneous pigmentation a.. Skin pigmentation induced by meropenem and levofloxacin.. Updated recommendations on the use of hydroxychloroquine in.. Skin Hyperpigmentation with Hydroxychloroquine Hydroxychloroquine Plaquenil is a common trade name is an anti-inflammatory oral medication that is commonly used to treat many autoimmune diseases. In the hair clinic, we use it for diseases such as lichen planopilaris, frontal fibrosing alopecia, An African American woman, aged 50 years, presents with painless “bruises” on her leg. with a blue-black to gray. Francès C, Piette J-C, et al. Hydroxychloroquine-induced pigmentation. Nov 25, 2017 Hydroxychloroquine is a common cause of drug induced hyperpigmentation. Unlike the lighter blue-grey color in chrysiasis, hydroxychloroquine induced hyperpigmentation is deeper grey-blue, grey-brown or black color that looks like bruises. Oral mucosal hyperpigmentation is a characteristic clinical feature which distinguishes it from chrysiasis.