He had a history of rheumatoid arthritis, and had been treated with hydroxychloroquine for the last 8 years. Echocardiography revealed a left ventricular ejection fraction of 25%, with diffuse hypokinesis. Hydroxychloroquine structure Does plaquenil work right away Heart problems like heart failure and a certain abnormal heartbeat prolonged QT interval have happened with Plaquenil hydroxychloroquine. Sometimes, these heart problems have been deadly. Sometimes, these heart problems have been deadly. Sep 13, 2017 We present a case of twin sisters who both suffered from systemic lupus erythematosus SLE and HCQ-induced cardiomyopathy presenting with decompensated heart failure HF, suggesting that genetic predisposition might be a factor in HCQ-induced cardiomyopathy. There is no Heart failure reported by people who take Plaquenil yet. This review analyzes which people have Heart failure with Plaquenil. It is created by eHealthMe based on reports from Food and Drug Administration FDA, and is updated regularly. eHealthMe has been monitoring drugs since 2008. The differential diagnosis for new onset non-ischemic cardiomyopathy in this patient included inflammatory cardiomyopathy, viral myocarditis, sarcoidosis, amyloidosis, hemochromatosis, Fabry's disease and HCQ toxicity. Coronary angiography demonstrated non-obstructive coronary disease. Treatment was initiated with guideline directed medical therapy, and patient clinically improved. Plaquenil and heart issues Will you have Coronary heart disease with Plaquenil - eHealthMe, Hydroxychloroquine-induced cardiomyopathy and heart failure. If hydroxychloroquine was ineffective would it be effective with methotrexateHydroxychloroquine accidental drug overdosePlaquenil cheapHydroxychloroquine wikik Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. While today it is used to treat autoimmune conditions, such as rheumatoid arthritis and lupus, it was originally used as an anti-malaria drug. Plaquenil Side Effects on Your Eyes and Vision. Will you have Heart failure with Plaquenil - eHealthMe. Common and Rare Side Effects for Plaquenil Oral. In rare cases, Plaquenil can cause cardiomyopathy, a chronic disease of the heart muscle. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few. Hydroxychloroquine HCQ-induced cardiomyopathy is one of the rare but severe complications following prolonged HCQ use. However, the exact mechanism of HCQ cardiotoxicity remains unclear and it is difficult to identify risk factors. We present a case. ATLANTA – Hydroxychloroquine Plaquenil 400 mg/day starting by pregnancy week 10 reduces recurrence of congenital heart block in infants born to women with anti-Ro antibodies, according to an open-label, prospective study presented at the annual meeting of the American College of Rheumatology.